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Indeed, experts have generally issued caution around doing aerobic exercise while in a calorie deficit due to the strain it can place on the body, which may result in breaking down muscle for energy

Doctronics approach aims to be faster, smarter, and more personal: fast answers drawn from current, peer-reviewed medical evidence

Dietary modifications, dose reduction, or slower titration may improve tolerability whilst maintaining therapeutic benefit

Anyone participating in a trial should follow the schedule set by their clinical team precisely, including guidance on what to do if a dose is missed, rather than making independent decisions about timing or frequency