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Description
GLP-1RAs increase natriuresis by inhibiting sodium reabsorption by acting on the Na/H exchanger in the proximal tubule of the kidney [75]

doi: 10.1002/ajmg.a.61391 94 YoungMFValarisSWrannCD
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Given the role of insulin, growth hormone, and sex steroids in pubertal maturation, pharmacological modulation of appetite and energy balance during this window may theoretically influence musculoskeletal development, bone mineralization, and long-term metabolic health

(2021) "Once-Weekly Semaglutide in Adults with Overweight or Obesity" The New England Journal of Medicine, 384(11) 5

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