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No serious adverse events apart from those associated with subcutaneous injections were reported in all three groups [13]

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In a study that was conducted to evaluate the role of oxidative stress in melasma, the levels of glutathione peroxidase enzyme activity and other pro-oxidant parameters were significantly higher in the blood of patients compared to controls

Also in 2017, Moderna researchers explored experimental mRNA vaccines in various animal models and found that mRNA vaccines injected intramuscularly activated protein production at the injection site, the spleen, the liver, and downstream lymph nodes (13)