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Unlike many therapeutic peptides, Dihexa can cross the blood-brain barrier and promote BDNF signaling , a key process for: These effects have made Dihexa of great interest in treating neurological diseases, age-related cognitive decline, and more recently, brain fog and fatigue

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Sleep 34 , 859867 (2011)

The clinical effects of these disorders depends on the severity of enzyme deficiency and whether the -glutamyl cycle also is affected in non-erythroid tissues

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Functional studies such as gain or loss-of function research are warranted to verify these findings further