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Potential pathways of the Lung-to-brain influence The lung-brain axis constitutes a complex interactive network that links pulmonary diseases and the CNS, collectively promoting the onset and progression of neurological disorders [261]

This finding is consistent with the broader observation that GHS-R1a receptors are expressed in multiple tissues beyond the pituitary, including kidney, heart, and immune cells, suggesting pleiotropic protective functions

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Gestational chronodisruption impairs circadian physiology in rat male offspring, increasing the risk of chronic disease

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