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As access to compounded GLP-1 injections recently became increasingly restricted, many patients turned to the gray market an underground network where medications are sold outs

Learn how to reset your GLP-1 response when weight loss stalls
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In November 2025, the Trump administration announced landmark agreements with Eli Lilly and Novo Nordisk reducing the monthly price of GLP-1 weight-loss drugs from over $1,000 to as low as $245 for eligible patients

Thus, the SELECT trial exceeded expectations (many commentators predicted the topline reduction to be likely sub-20%), but also underlined the need for further outcomes trials to clarify other potential benefits, as well as, for competitors, meeting or exceeding the performance of Wegovy
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