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The question then arises: What is the explanation for this unique apparent regulation of Se-GSH-Px by organic selenium? Regulation of the GSH-Px system The glutathione (GSH) system, comprising oxidized and reduced GSH and the two enzymes GSH peroxidase and GSH reductase, is closely related to the metabolism of two amino acids, cysteine (Cys) and methionine (Met) (Figure 3) via the key intermediary metabolite, homocysteine

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It was observed that orally administered LU-SLNs were absorbed more rapidly than pure luteolin suspension, evidenced by a shorter time to reach maximum concentration ( T max ) [224]

Fundamental discoveries include the identification of specific cellular structures, such as the vulnerable hair cells within the inner ear as primary targets of noise-induced damage (7)

The net effect of this checkpoint signaling likely varies by cellular context and disease stage (142)

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