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Gastrointestinal changes are among the most commonly reported effects

Possible Side-Effects of Semaglutide During the increase in dosage, patients should be aware of any unwanted side effects such as: Loss of appetite (i.e., constant feelings of fullness that go beyond the desired results) Light-headed or dizzy sensations Persistent lethargic feeling Gastrointestinal discomfort Diarrhea Before starting semaglutide or any other medication, its crucial for patients to discuss their medical history and any existing health conditions with their medical weight loss doctor

doi: 10.1037/amp0000517

Based on the available evidence, cagrilintide appears to have a more favorable body composition profile, though the magnitude of difference between the two compounds remains to be determined through direct comparison studies

GLP-1 RAs differ in their pharmacokinetic and pharmacodynamic properties, and recently developed agonists have a longer duration of action than endogenous GLP-1 RAs and the first synthetic GLP-1 RA, exenatide (29)