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Among the exendin 939 fragments, exendin 2029 specifically binds to TRPV1, alleviating pain in both acute and chronic pain models without interfering with GLP-1R function

Outcomes vary: Mild cases may improve with treatment Moderate cases may require long-term management Severe cases can become permanent Some patients develop lifelong GI dysfunction after GLP-1 drug use Early diagnosis significantly improves prognosis

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