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Glymour, M

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The pharmacokinetics are fundamentally different, and those differences drive every dosing decision you will make

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In vivo imaging demonstrated that ITP-modified lipid nanoparticles efficiently delivered Cy5-siBACE1 to the brain and enhanced the stability of Cy5-siBACE1 28 (Supplementary Fig

It may also be a more practical choice for long-term maintenance therapy
