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Here is the arithmetic, shown step by step, for the two most common vial configurations

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Example-21: Preparation of compound of formula-17 DMAP (25.24 gm) and t-butanol (130 ml) were added to a mixture of toluene (1170 ml) and compound of formula-16 (130 gm) at 25-30C

The percentage of prescriptions filled within 5 days of being written reached their lowest values in March 2023, a decrease of 10.6 percentage points, compared to the three months before the shortage started