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In brief, 10 L CellTiter 96 AQ ueous One Solution Reagent was added to each well

CRISPR/Cas9-mediated targeting of ABCC1 in Cas9-expressing THP-1 cells using multiple sgRNAs re-sensitized them to BCL-2 inhibition, as ABCC1 -targeted cells were rapidly depleted upon Venetoclax treatment (Fig

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Within cells, GSH exists in a balanced ratio of the reduced sulfhydryl form (GSH) and the oxidized glutathione disulfide form (GSSG)
