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Indeed, supersulfides exhibit superior nucleophilicity and reducing capacity when compared to their corresponding parental thiols [53,54,55]

HIV-1 decreases Nrf2/ARE activity and phagocytic function in alveolar macrophages

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doi: 10.1080/15622970701227811

502 Moreover, neutrophils and NETs damage the glycocalyx of endothelial cells and increase endothelial permeability, which may further lead to dysregulated inflammation, impaired microcirculatory blood flow, inadequate tissue perfusion, and life-threatening organ failure