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Furthermore, these cohorts represented populations with relatively mild disease severity proxies, indicated by low rates of prior advanced therapy use

They point out that some children could experience trauma from being told that their bodies are diseased and that they must consume medications to fix them

The most significant contributor is improved glycemic control in patients with type 2 diabetes

Higher body weight may affect the volume of distribution, though standard dosing protocols generally account for this variation

doi: 10.1161/CIR.0000000000001209