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This had never been done before because it has been very difficult and laborious to obtain the pure enzymes, but this study was now enabled by our recent method development to produce recombinant selenoproteins with internal Sec residues, such as the GPX isoenzymes

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The aggregate literature highlights the need for better and more quantitative tools along with the importance of compartmentalization (e.g., cytosol vs

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Molecular and Cellular Biology, 17 (9)

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