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Call 911 or go to the emergency room if you experience severe abdominal pain (especially if radiating to your back), persistent vomiting, signs of dehydration, confusion, difficulty breathing, or if you cannot reach your healthcare provider when experiencing concerning symptoms

Patients should discuss these risks with their doctor before beginning a semaglutide drug regimen

That last point matters more than it sounds: existing oral semaglutide (Rybelsus) must be taken 30 minutes before eating, with only a small amount of water, a barrier that can be frustrating in real life

And that could lead to new treatments for alcoholism and other substance use disorders

If you experience a related symptom, treat it as an emergency

Patients must wait 30 minutes before eating, drinking, or taking other medications