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Discontinuation and Duration Dependent Cardiovascular Risk Compared with continual use of GLP-1s, discontinuing treatment for 6 months was associated with a 4% increased risk of major adverse cardiovascular events

Nausea and Dehydration with Semaglutide Semaglutide-based weight loss medications are well known for causing gastrointestinal side effects, especially during the initial weeks

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Conclusion Semaglutide offers hope to those who have been struggling with weight loss

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But the similarity ends there, because their mechanisms of action diverge in fundamental ways that directly impact fat loss outcomes , metabolic health, and long-term body composition