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Many compounds have been developed to convert the mutant p53 protein into a WT p53 conformation, thereby restoring some WT p53 functions

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miR-34a regulates lipid metabolism by targeting SIRT1 in non-alcoholic fatty liver disease with iron overload

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Some of the substances are classified as hard narcotics, like heroin, but the use of these is very limited as they are usually not commercially available

PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53