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They are usually mild, short-lived, and do not require medical attention

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Skye Bioscience Phase 2a data show added weight loss with nimacimabsemaglutide combination Skye Bioscience has reported topline results from its Phase 2a CBeyond study evaluating the peripherally acting CB1 inhibitor nimacimab in adults with overweight or obesity, showing clinically meaningful additional weight loss when combined with semaglutide, but not when used alone at the tested dose

N Engl J Med 384(11):9891002 [DOI] [PubMed] [Google Scholar] 22.Wilding JPHBR, Calanna S, Van Gaal LF, McGowan BM, Rosenstock J, Tran MTD, Wharton S, Yokote K, Zeuthen N, Kushner RF (2021) Impact of semaglutide on body composition in adults with overweight or obesity: exploratory analysis of the STEP 1 study
