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Aetna's clinical team reviews it and either approves or denies the request

While meta-analyses of randomized controlled trials suggest a potentially increased risk of biliary diseases with DPP-4 inhibitors globally [13, 30], the absolute risk in Japanese populations appears unknown

Some people might see the initial effects sooner, like a reduced appetite, which is a good sign the medication is working

Under normal circumstances, however, this is short-term

Current guidance derives from animal research, early human trials, and anecdotal experience from research communities

Actual costs vary based on dosage, dispensing channel, and prescription specifics