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GLP-1 has different effects on left ventricular function and cardiac contractility under healthy vs

People with certain medical conditions, including a history of pancreatitis or thyroid cancer, may not be good candidates, and should speak with their doctor to decide what management strategies are right for them

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This is one of the most common and most counterintuitive causes

In rare cases, GLP-1 agonists may cause serious side effects, including allergic reactions, pancreatitis, gallbladder disease, and kidney disease.[ref][ref] Obviously, talk with your doctor about the risks vs
