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24,25 The average pain NRS- score significantly improved from 6.9 to 4.5 after treatment (p = 0 .027)
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For these reasons, new proximity labeling enzymes that use different chemistries than existing enzymes are needed to advance the field
Furthermore, noteworthily on the metabolic benefits, ketogenic diets seemed to increase BDNF in the hippocampus, associated with improvements in synaptic stability, and a reduction in acute seizure related to epilepsy [252]
However, this does not invalidate other mechanisms such as changes in lysosomal pH during stress [54]
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