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Rather than randomizing individuals with T2D and established CVD to placebo, participants received either tirzepatide or dulaglutide, with the assumption that dulaglutide preserved a cardiovascular benefit of at least 12% over placebo as observed in REWIND

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However, BSH activity has been detected in various other gastrointestinal bacteria but not in A

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The study used de-identified electronic health record (EHR) data from Truveta to compare weight-loss outcomes and changes in cardiometabolic changes over six months

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Multiple randomized controlled trials show that adding GLP-1 agonists to metformin reduces A1C by an additional 0.51.5% and promotes weight loss of 25 kg over 6 months compared to metformin alone

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