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Several studies have further observed that introducing high concentrations of H 2 O 2 to Mn 3+ SOD leads to the formation of the inhibited complex that decays to Mn 2+ SOD 26,50,51,52

This antioxidant effect also stabilizes mitochondrial membranes, preventing the release of apoptogenic factors in -cells and other insulin-sensitive tissues (Papuc 2022)

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PMC 2544566

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