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2022;21:32 Liu T, Zhu C, Chen X, Guan G, Zou C, Shen S, et al

Lyon and Dr

To critically appraise mechanisms and levels of evidence ( in vitro, in vivo , clinical) for vitamin E and C, glutathione and its precursors, polyphenols (quercetin, resveratrol, curcumin), Crocus sativus carotenoids (crocin/safranal), and indirect modulators (e.g., omega-3, folinic acid), emphasizing study quality, translational relevance, and limitations

One possible issue is the formation of cysts, bumps, lumps, or skin irregularities in the treated area
