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Semaglutide may worsen diabetic retinopathy in some patients with pre-existing disease

Intrinsic Neural Deficits Neurologic disorders such as Parkinsons disease, amyloidosis, dysautonomia, and diabetic neuropathy are theorized to affect both intrinsic and extrinsic neural pathways

Aroda VR, Ahmann A, Cariou B, et al

doi: 10.1111/j.1748-1716.1993.tb09596.x 172 MeyerMRCleggDJProssnitzERBartonM

Lots of GLP-1 users can currently afford their prescriptions thanks to cheaper, compounded versions being available while branded drugs are in short supply

Discontinuation often leads to weight regain, making long-term maintenance challenging