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Description
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One obvious explanation for the low ratio of [GSH]:[GSSG] is that Ero1 activity leads to the oxidation of GSH

For studies focused on different absorption pathways, particularly gastrointestinal routes, other forms exist

Environ Sci Pollut Res Int 25(12):1217712182 Denison MS, Soshilov AA, He G, Degroot DE, Zhao B (2011) Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor

In the brain, there are three major isoforms of RAS
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