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NodThera is targeting these inflammatory drivers of obesity in the brain to restore homeostasis, thereby addressing dysregulation of the hypothalamic setpoint, a fundamental pathological feature of people living with obesity

Stability varies by peptide and solvent

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These drugs have been used to treat type 2 diabetes for nearly two decades, with the first GLP-1 medication, exenatide, gaining FDA approval in 2005

Due to its action on the central nervous system, tesofensine should be used cautiously, especially by individuals with pre-existing cardiovascular conditions
