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After the addition of FeCl 3 the colour of the reaction mixture turned quickly to brown, indicating the formation of FeS clusters

To assess transcriptional alterations across MS lesion types, we performed pseudobulked differential gene expression analysis comparing MOLs from each MS lesion type to control WM (Supplementary Data 6)

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Furthermore, C11 BODIPY staining and western blot results confirmed the impact of the SOX4/EZH2 axis on ferroptosis