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[DOI] [PubMed] [Google Scholar] 149.Rssner S, Barkeling B, Erlanson-Albertsson C, Larsson P, Whlin-Boll E

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What is AOD-9604 and How Does It Work Without Affecting Appetite

Unlike NAD+ precursors that work downstream, 5-Amino-1MQ acts upstream by blocking NNMTs consumption of S-adenosyl methionine (SAM), resulting in elevated intracellular NAD+ and SAM levels without requiring direct nucleotide supplementation
High doses are generally considered safe, though some people may experience minor side effects

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