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This shortage is why FDA is allowing both semaglutide and tirzepatide to be compounded, despite being under patents

These symptoms are often observed during the initial weeks of treatment

N Engl J Med 2017;377:13-27

Medication review : Assess for concurrent medications that may increase stone risk (loop diuretics, topiramate, acetazolamide, triamterene, indinavir, high-dose vitamin C, and vitamin D supplements, particularly when combined with calcium supplementation)