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Description
Case of zinc deficiency-induced dermatomyositis-like dermatitis: Association between absence of CD1a-positive Langerhans cells and development of dermatitis

But older skin also has reduced baseline resilience and may need gentler introduction protocols

Allergy-wise, there are some case reports on neem oil causing allergic contact dermatitis so people with plant/botanical sensitivities may want to patch test first

10.1038/s41578-021-00279-y 96 HferT.GernerI.Gundert-RemyU.LiebschM.SchulteA.SpielmannH.et al (2004)

These intake levels are well below the RDA of 15 mg/day (see the RDA)

Wing, K
