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The hazard ratio for all-cause mortality was 0.94 (95% CI: 0.78-1.13)

The medication's appetite-suppressing effects often lead to reduced food intake and altered dietary patterns

However, under most circumstances, it is not feasible to wait for 60 min on an empty stomach in the morning, and as an alternative, levothyroxine could be taken before going to bed (possibly at least 3 hours after the last meal of the day)

Impaired endometrial receptivity Glucagon-like peptide-1 receptors have been identified in endometrial tissue and may influence proliferation and inflammatory pathways relevant to implantation

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The SELECT trial (2023) in non-diabetic patients with obesity and established CVD reported a 20% MACE reduction (HR 0.80, 95% CI 0.720.90), driven by reductions in MI and stroke, marking a paradigm shift for GLP-1 agonists in primary prevention [12]