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For example, in animals calcium deprivation enhanced absorption of lead and cadmium [69], while magnesium and zinc supplementation blunted absorption of cadmium [2]
Early detection and treatment of B12 deficiency are important

The effectiveness per milligram is lower because oral bioavailability is significantly less than injectable

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Conceivably, the elimination of PDPN + cells in the MB TME may reduce the immunosuppression exerted by different types of mesenchymal stromal cells allowing the triggering of NK or T cell responses as shown in other tumor models (278281)
