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14.2 Monotherapy Use of RYBELSUS in Patients with Type 2 Diabetes Mellitus In a 26-week double-blind trial (Trial 1, NCT02906930), 703 adult patients with type 2 diabetes mellitus inadequately controlled with diet and exercise were randomized to RYBELSUS 3 mg, RYBELSUS 7 mg or RYBELSUS 14 mg once daily or placebo

Published August 2025

It was confirmed that the variant for greater weight loss effectiveness and the variant for side effects tend to act together, meaning that a better drug response was often accompanied by more severe nausea

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While their effects may be less dramatic than pharmaceutical drugs, their sustained and gentle action, coupled with easier accessibility and often lower cost, makes them attractive for long-term health maintenance and preventive care