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Description
The data supports continued use in: Type 2 diabetes Obesity and metabolic syndrome Patients with cardiometabolic risk factors Reasonable caution is still appropriate in individuals with: Active pancreatitis Recurrent idiopathic pancreatitis Severe hypertriglyceridemia until corrected
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Cryo-EM analysis of a complex involving an exendin-4 analogue, the GLP-1R and Gs protein revealed two receptor conformers with distinct modes of peptide-receptor engagement
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