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GH plays a multifaceted role in the human body, primarily influencing body composition by increasing muscle mass, reducing fat tissue, promoting bone formation, and regulating the metabolism of proteins, lipids, and glucose

Regorafenib enhances anti-tumor efficacy of immune checkpoint inhibitor by regulating IFN-/NSDHL/SREBP1/TGF-1 axis in hepatocellular carcinoma

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doi: 10.1093/cid/ciy776 10 BenitezL

It changes the metabolic environment in ways that make the body more effective at using fat as fuel and less prone to storing excess energy as visceral adipose tissue