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Only 4 of the 30 people regained weight and chose to return to weekly dosing
Mauran, L., Kauffmann, B., Odaert, B

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Currently, orforglipron has not been approved for use in the UK, but approval for use in the US has been granted so its likely

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Risk of fracture with dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: A systematic review and network meta-analysis combining 177 randomized controlled trials with a median follow-up of 26 weeks
