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Although alterations in genetic factors have been linked with its etiology, exponential accumulation of environmental entities such as reactive oxygen species (ROS) initiate a cyclic chain reaction resulting in accumulation of cellular inclusions, dysfunctional mitochondria, and overwhelming of antioxidant machinery, thus accelerating disease pathogenesis

Alternatively, if there is still quite a bit of your protein in the flow-through then you could use even more resin next time to capture more of your target protein (Figure 5, right)

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It is not intended for use in humans or animals and must not be used for therapeutic, diagnostic, or clinical purposes