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This is particularly relevant on GLP-1 medications, where the primary issue is slowed gastric emptying

By the time you get home and realize the medication should be refrigerated, the clock has already started ticking

3 GADPH = Glyceraldehyde- 3-phosphate dehydrogenase, 4 MMP-1/3/13 = matrix metalloproteinase 3/13

In contrast, CNS, but not vagal, GLP-1Rs were required for a complete anorectic response to the long-acting GLP-1R agonist liraglutide and the anorectic and weight loss effects of chronic liraglutide treatment

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