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Continued research will be required to examine the long-term safety implications of DPP-4 inhibitors, as well as to discover off-target and congeneric clinical applications in order to fully realize these advantages
The SURMOUNT-1 trial was a 72-week, phase 3, randomized, double-blind, multicenter clinical trial that evaluated three tirzepatide doses vs

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[DOI] [PubMed] [Google Scholar] 17.Malhotra A, Grunstein RR, Fietze I, Weaver TE, Redline S, Azarbarzin A, et al
Tanaka (89) reported through clinical studies that GLP-1RA in combination with metformin could inhibit the proliferation and induce the apoptosis of breast cancer cells
