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Targeting downstream signaling pathways to TLRs recapitulates the effect of TLR-knockout on the promotion of K-ras driven lung cancer by COPD-like airway inflammation To further dissect the cell type specific mechanism of tumor promotion by TLR activation in a COPD setting, we studied the signaling checkpoints shared among TLRs, specifically MyD88/NF-B signaling

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Host and Microbe 22 (4), 519530.e3