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Research has shown that chronic receptor start can trigger feedback mechanisms that reduce receptor expression or alter signaling efficiency
According to some investigations by Brentjens and Curran's groups, primary chemotherapy with cyclophosphamide (CTX) drastically increases the persistence and response of CAR19-T cell [21]
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[DOI] [PubMed] [Google Scholar] 55.Vairetti M, Di Pasqua LG, Cagna M, Richelmi P, Ferrigno A, Berardo C: Changes in Glutathione Content in Liver Diseases: An Update
