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as mentioned, the animal study by Zhang 2015 found reduced DNA fragmentation in sperm of GLP-1-treated mice, hinting at a protective effect on sperm DNA perhaps via less oxidative stress or inflammation

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Another study has reported that treatment of the DPP-4 inhibitor vildagliptin (10 mg/kg) in STZ-induced diabetic rats suppresses plasma TNF- concentrations and inhibits nitric oxide concentrations in the serum ( In the brain, GLP-1 treatment has a preventive effect on the progression of Alzheimers disease pathology in rats (Iwai et al., 2014

Lawsuits allege that patients who took these peptides suffered severe health issues, including gastrointestinal injuries and other complications