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doi: 10.2337/dc16-0690 57 MathieuCZinmanBHemmingssonJUWooVColmanPChristiansenEet al
Location, location, location: compartmentalization of NAD(+) synthesis and functions in mammalian cells

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PFK1 is one of the three rate-limiting enzymes for glycolysis and enhances glycolysis by increasing fructose-1,6-bisphosphate (F-1, 6-BP) biosynthesis and glucose uptake [49]