oral glp-1 agonists approved for clinical use. GLP-1 agonists are available Another milestone in the evolution

GLP-1 is a target for treatment of diabetes because of the primary peripheral functions of inducing insulin secretion from pancreatic cells, gut emptying and inhibiting glucagon secretion which results in lower blood glucose levels ( GLP-1 can also be produced by neurons in central nervous system (CNS) ( Pathogenesis of AD Amyloid plaque Amyloid beta (A) is a peptide with a molecular weight of 4 KDa and a length of 40-42 amino acids ( 2+ channels and AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors, to which the neurotransmitter glutamate binds, so A is the most neurotoxic form ( Neurofibrillary tangles Tau is a microtubule-associated protein and mainly found in the axonal compartment ( Synaptic dysfunction and neurotransmitter imbalance It has been well established that cholinergic transmission is essential for memory, learning, attention, and other higher brain functions, so cholinergic deficits play a key role in the neuropathology of AD ( Neuroinflammation Neuroinflammation, microglia activation in response to amyloid deposition, plays a central role in the pathogenesis of AD ( Insulin resistance For the past few years, AD has also been considered as type 3 diabetes because of insulin resistance (IR) and dysregulation of insulin signaling in the brain ( is mainly transported across the BBB

Martinez de Tejada Weber, Genve (Gyncologie-obsttrique)

GLp-1 receptor agonists and risk for cirrhosis and related complications in patients with metabolic dysfunction-associated steatotic liver disease

Shahaits academic prowess is further reflected in his editorial roles across various esteemed urological journals.

There is no magic bullet for obesity

*Correspondence: Hao Liu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers