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Antagonists of G-protein-coupled receptor family C group 6 subtype A (GPRC6A) abolished the additive effect of ornithine on preference for MSG solutions in both behavioral and electrophysiological experiments, suggesting that ornithine is a kokumi substance that binds to another possible kokumi receptor, GPRC6A

J Biomed Sci 19:32

10.1038/s42004-024-01182-7 91 ZhangZ.LuoT.YanM.ShenH.TaoK.ZengJ.et al (2025)

& Blanpain, C

Benjamin J, Makharia G, Ahuja V, et al

175 Traditional agents like ginger and peppermint, though not elaborated in the primary dataset, have been widely cited (e.g., Brierley & Kelber, 2011) for their ability to regulate motility through TRP channel modulation and calcium channel blockade