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They also function as redox hubs, contributing significantly to intracellular ROS pools

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In addition to our literature review, an animal model study has shown that amlodipine inhibits AGEs deposition in the inner membrane of the aorta, despite the absence of a statin effect on plasma lipids 97

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In contrast, high hypoxia-inducible lipid droplet associated protein levels in established HCC reduce ceramide production, helping HCC cells evade apoptosis [202] and promoting tumor progression

NCT06629909, not yet recruiting, Phase I) are registered on ClinicalTrials.gov for using MSC-EVs in liver fibrosis/cirrhosis (Fig