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Grimm M, Han J, Weaver C, Griffin P, Schulteis CT, Dong H, Malloy J (2013) Efficacy, safety, and tolerability of exenatide once weekly in patients with type 2 diabetes mellitus: an integrated analysis of the DURATION trials

A multidisciplinary panel of endocrinologists recently advised clinicians to extend the dose-escalation phase or pause dose increases if patients are experiencing GI adverse effects (source)

This catches early organ stress while your body adjusts to the medication
While the benefits can be life-changing, the weekly routine can be a challenge

[DOI] [PubMed] [Google Scholar] 271.Nielsen L.B., Ploug K.B., Swift P., Orskov C., Jansen-Olesen I., Chiarelli F

If you travel frequently and time zones change your sleep schedule, morning injection often adapts more easily to shifting schedules
