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So I guess its kind of trial and error to see what helps, so all of these replies and info are so helpful to help me to discuss with my GP and work through

This NAD+ elevation activates sirtuins (particularly SIRT1), enhances mitochondrial function, and preserves methylation capacity by reducing S-adenosylmethionine (SAM) consumption

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Materials and Methods: Thirty-six male mice were randomly divided into six groups

not too little, not too much

Ensure it is kept out of reach of children